Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Chordata (incl. vertebrates e.g. mammals and birds)
Mammalia (mammals)
Rodentia (rodents)
Muridae (mice, rats, and gerbils)
Mus (mice)
House mouse
Readiness of Technology
4a - Active research on gene drive constructionPublications
Intended use
Eradicating invasive populations on islands to address biodiversity impacts
Type of system
T-haplotype sex ratio distorter (carrying Sry cargo)
House mouse
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Eradicating invasive populations on islands to address biodiversity impacts
Type of system
T-haplotype sex ratio distorter (carrying Sry cargo)
House mouse
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Eradicating invasive populations on islands to address biodiversity impacts
Type of system
T-haplotype sex ratio distorter (carrying Sry cargo)
House mouse
Readiness of Technology
4a - Active research on gene drive constructionPublications
Intended use
‘eradicating mice from islands’ or at continental scale [presumably Australia] to address their impacts on biodiversity
Type of system
CRISPR based X-shredder gene drive (‘driving Y’)
House mouse
Readiness of Technology
4a - Active research on gene drive constructionPublications
Intended use
The production of complex strains harboring multiple humanizing genes
Type of system
Split gene drive system - multiple configurations tested
Rattus (rats)
Polynesian rat
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To eradicate invasive populations in New Zealand to prevent predation of native species.
Type of system
Homing CRISPR
Polynesian rat
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To control/ eliminate invasive populations on islands
Type of system
Not specified – t-haplotype and homing CRISPR both mentioned
Brown rat
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Eradicating invasive rat populations on islands to address their impacts on biodiversity
Type of system
Homing CRISPR (targeting ‘haplosufficient female fertility gene’ or ‘haplosufficient zygote viability gene’) and ‘Y-shredder’ (located on X-chromosome)
Brown rat
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To eradicate invasive populations in New Zealand
Type of system
Homing CRISPR
Brown rat
Readiness of Technology
1 - Gene drive proposedIntended use
‘to curb pest rodent populations’
Type of system
Homing CRISPR (targeting ‘haplosufficient female fertility gene’)