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Proposed homing CRISPR gene drive targeting female fertility in Rattus norvegicus - University of Edinburgh
Rattus norvegicus
Brown rat
Intended use
‘to curb pest rodent populations’
Readiness of Technology
1 - Gene drive proposed
Project leader
Whitelaw CBA
Institution
Roslin Institute, University of Edinburgh, UK
Project leader
Lillico SG
Institution
Roslin Institute, University of Edinburgh, UK
Publications
Roslin Institute, 2017
McFarlane, Whitelaw and Lilico, 2018
Authors name for system
Homing gene drive targeting female fertility
Class of Technology
Homing gene drive
Field(s) of application
Other
Description of system
Homing CRISPR (targeting ‘haplosufficient female fertility gene’)
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population suppression/eradication