Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Diptera (true flies)
Culicidae (mosquitoes)
Culex (typical mosquitoes)
Southern house mosquito
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of transmission of vector borne diseases in humans, mammals and birds (e.g. avian malaria)
Type of system
Split homing CRISPR
Southern house mosquito
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of transmission of vector borne diseases in humans, mammals and birds (e.g. avian malaria)
Type of system
Unspecified - CRISPR based
Western Encephalitis Mosquito
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction in transmission of arboviruses (e.g. West Nile virus) in humans and horses by this vector
Type of system
Unspecified gene drive + sex ratio distorter
Drosophilidae (fruit flies)
Drosophila (fruit flies)
Spotted winged drosophila
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to soft fruit crops (e.g. cherries) caused by this species
Type of system
Medea gene drive
Spotted winged drosophila
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to soft fruit crops (e.g. cherries) caused by this species
Type of system
Propose homing CRISPR
Spotted winged drosophila
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to soft fruit crops (e.g. cherries) caused by this species
Type of system
Split homing CRISPR
Spotted winged drosophila
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction of economic costs caused by consumption of fruit crops by this species.
Type of system
NA- Stakeholder engagement study
Spotted winged drosophila
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to soft fruit crops (e.g. cherries) caused by this species
Type of system
Homing gene drive targeting Tyrosine decaroxylase 2 (Tdc2) - a recessive female fertility gene
Spotted winged drosophila
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to soft fruit crops (e.g. cherries) caused by this species
Type of system
Homing CRIPSR gene drive targeting transformer gene
Glossinidae
Glossina
Tsetse flies
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction in transmission of trypanosome parasites by this vector (to reduce occurrence of sleeping sickness in humans and livestock, esp. European cattle breeds.)
Type of system
NA – proposal only