Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Chordata (incl. vertebrates e.g. mammals and birds)
Hyperoartia (jawless fish)
Petromyzontiformes (lamprays)
Sea lamprey
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Options proposed include: Split homing CRISPR ; ‘Y-Linked X-shredder’ ; Homing CRISPR ; Toxin Antidote
Sea lamprey
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Homing CRISPR
Sea lamprey
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
sex ratio distorter causing "daughterless" phenotype
Sea lamprey
Publications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Various CRISPR based options proposed including ' A homing-type drive targeting lamprey sex-determining or gametogenic genes' and 'integrating daisy-chain architecture with small-molecule contrrol elements'
Mammalia (mammals)
Artiodactyla (Deer and related mammals)
Deer
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
To render the wild population immune to chronic wasting disease [by spreading PRNP null alleles]
Type of system
Homing CRISPR
Feral pig
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To address the 'social, economic and environmental burden' of this non-native species in Australia
Carnivora (Cats, dogs and related mammals)
House cat
Readiness of Technology
2b - Gene drive proposed with preliminary laboratory work fundedPublications
Intended use
To eradicate or control feral cats in Australia to reduce predation of native species
Type of system
Not stated
House cat
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Eradication at continental scale, presumably in Australia, to address impacts on biodiversity
Type of system
Homing CRISPR or ‘Y-linked X shredder’- Y-chromosomelinked X-chromosome shredding drive
House cat
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Eradication or control of feral cats in Australia to address their impact on biodiversity, i.e. native fauna.
Type of system
Homing CRISPR
Stoat
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To control or eradicate this invasive species in New Zealand to reduce predation of native birds including kiwis
Type of system
Homing CRISPR