Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Lepidoptera (moths, butterflies and skippers)
Noctuidae (owlet moths)
Spodoptera (armyworms)
fall armyworm
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Prevention of damage to crops by this pest species
Type of system
Proposed homing CRISPR gene drive
Plutellidae (diamondback moths)
Plutella
Diamond back moth
Readiness of Technology
4a - Active research on gene drive constructionPublications
Intended use
Reduction of damage to cruciferous crops by this species
Type of system
Split homing CRISPR
Diamond back moth
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to cruciferous crops by this species
Type of system
Unspecified
Diamond back moth
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to cruciferous crops by this species
Type of system
Not specified but study uses CRISPR-Cas9 gene knockout methodology, so homing CRISPR seems likely
Diamond back moth
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Demonstration of a functional homing CRISPR gene drive system in this species, to allow development of systems for ‘genetic control of globally distributed pest P. xylostella'
Type of system
Homing CRISPR
Pyralidae (pyralid or snout moths)
Plodia (Indian meal moth)
Indian meal moth
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction of damage to dry food stores (e.g. cereals) caused by this species
Type of system
NA – proposal only
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Thysanoptera (thrips)
Thrips
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Reduction of damage to crops caused by thrips
Type of system
Homing CRISPR
Chordata (incl. vertebrates e.g. mammals and birds)
Actinopterygii (bony fish)
Cichliformes (incl. cichlids and leaffishes)
Nile tilapia
Publications
Intended use
To reduce the biodiversity impacts of invasive populations of this species
Type of system
Proposed gene drive - homing CRISPR (or 'driving Y')
Cypriniformes (carps, minnows and related fish)
European carp
Readiness of Technology
4a - Active research on gene drive constructionIntended use
Control of invasive populations of this species
Type of system
Unspecified
Scorpaeniformes (lionfishes and related fish)
Red lionfish
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
To control or eradicate this invasive species to address damaging impacts to native reef communities in Caribbean and Western Atlantic
Type of system
Homing CRISPR