Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Diptera (true flies)
Tephritidae (fruit flies)
Ceratitis (includes the Mediterranean fruit fly)
Mediterranean fruit fly (or medfly)
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to fruit crops caused by this species
Type of system
Homing CRISPR
Mediterranean fruit fly (or medfly)
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to fruit crops caused by this species
Type of system
Preliminary study only, but development of CRISPR methods in this species points towards CRISPR based gene drive design.
Mediterranean fruit fly (or medfly)
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to fruit crops caused by this species
Type of system
Homing gene drives targeting white-eye gene and disrupting transformer (tra) in trans, OR targeting tra directly
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Hemiptera (true bugs)
Silverleaf whitefly
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Reduction of damage to crops caused by transmission of begomoviruses by this vector species
Type of system
Homing CRISPR
Silverleaf whitefly
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction of damage to crops via feeding or transmission of viruses (especially begomoviruses)
Type of system
Homing CRISPR (probably)
Silverleaf whitefly
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To prevent damage to cotton crops from this species
Type of system
Proposed homing CRISPR gene drive
Asian citrus psyllid
Readiness of Technology
X - Abandoned projectPublications
Intended use
Reduction in transmission of citrus greening disease, and resulting harm to citrus fruit. This species acts as a vector for Candidatus Liberibacter spp. bacteria which cause the disease.
Type of system
Not stated – no details of design published
Asian citrus psyllid
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction in transmission of citrus greening disease, and resulting harm to citrus fruit. This species acts as a vector for Candidatus Liberibacter spp. bacteria which cause the disease.
Type of system
Propose homing CRISPR
Western tarnished plant bug
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction in damage to cotton and other crops caused by this species
Type of system
Probably CRISPR based – various forms of CRISPR drive cited
Kissing bug
Readiness of Technology
2b - Gene drive proposed with preliminary laboratory work fundedPublications
Intended use
Reduction in transmission of the parasite Trypanosoma cruzi by this vector (to reduce occurrence of Chagas disease)
Type of system
Propose homing CRISPR