Homing CRISPR variant in Anopheles gambiae - 'Integral gene drive' targeting nanos - Imperial College

Intended use

Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)

Project leader

Windbichler N

Institution

Imperial College London UK

Publications

Authors name for system

nanosd integral gene drive

Class of Technology

Homing gene drive

Field(s) of application

Vector control

Additional notes

The nanosd construct has no cargo, but can be used to promote super-mendelian inheritance of a separate construct encoding 'anti-malarial' peptides.

Description of system

Homing CRISPR variant - 'Integral gene drive' targeting nanos

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement