Homing CRISPR for population modification in Anopheles arabiensis - UC Irvine

Intended use

Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)

Readiness of Technology

5 - Limited proof of concept in laboratory

Project leader

James AA

Institution

University of California Irvine

Project leader

Carballar-Lejarazú R

Institution

University of California Irvine

Publications

Authors name for system

'AgNos-Cd1'

Class of Technology

Homing gene drive

Field(s) of application

Vector control

Description of system

Homing CRISPR targeting the Agcd (cardinal) gene

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement