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Split homing CRISPR gene drive in Candida albicans - MIT & University of Guelph
Candida albicans
Intended use
To create single and double deletion mutants in this species for laboratory studies.
Readiness of Technology
6 - Laboratory proof of concept
Project leader
Collins JJ
Institution
MIT, USA
Project leader
Shapiro RS
Institution
University of Guelph, Canada
Publications
Shapiro et al., 2018
Halder et al., 2019
Authors name for system
CRISPR-Cas9 based gene drive
Class of Technology
Split homing gene drive
Field(s) of application
General research and development
Additional notes
It is uncertain if research has indeed progressed to the stage of laboratory proof of concept
Description of system
Split homing CRISPR
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population modification/replacement