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'Z linked W-shredder' gene drive in Schistosoma genus - MIT & George Washington University
Schistosoma genus
Blood fluke
Intended use
To suppress schistosome parasites to thereby reduce human morbidity and mortality from schistomiasis
Readiness of Technology
4a - Active research on gene drive construction
Project leader
Esvelt KM
Institution
MIT, USA
Project leader
Brindley P
Institution
George Washington University, USA
Publications
AAAS, 2016
Holman, 2019
Authors name for system
One proposal would be a Z linked ‘W-shredder’ (as described by Holman, 2019); ‘all of the offspring will be born either female or male.’ (AAAS, 2016)
Class of Technology
Other gene drive system
Sex ratio distorter
Field(s) of application
Vector control
Additional notes
No results have been published
Description of system
Z linked W-shredder, with variable parameters (as described by Holman, 2019)
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population suppression/eradication