Preliminary work towards homing CRISPR gene drive in Biomphalaria glabrata - Stanford University

Intended use

To modify snail populations to increase their immunity to schistosome infection, thereby disrupting the schistosome lifecycle and reducing transmission to humans

Readiness of Technology

2a - Gene drive proposed with supporting theoretical work

Project leader

De Leo GA

Institution

Stanford University, USA

Publications

Grewelle et al., 2022

Authors name for system

CRISPR gene drive

Class of Technology

Homing gene drive

Field(s) of application

Vector control

Description of system

Homing CRISPR

For specialists

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement