Preliminary work towards a homing CRISPR gene drive in Thysanoptera - Peking University

Thrips

Intended use

Reduction of damage to crops caused by thrips

Readiness of Technology

2a - Gene drive proposed with supporting theoretical work

Project leader

Champer J

Institution

Peking University

Publications

Authors name for system

NA – proposal only

Class of Technology

Homing gene drive

Field(s) of application

Agriculture

Description of system

Homing CRISPR

Description

Homing CRISPR gene drive targeting a haplo-sufficient female fertility gene.

Notes on readiness of technology

Modelling study suggests feasibility of targeting haplodiploid species with a suppression drive targeting female fertility.

This species is given as an example of a possible target amongst others.

Phenotype

Female infertility in homozygotes.

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication