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Tracking plans to genetically modify wild species
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Homing CRISPR gene drive in Mus musculus, part of study into population modification in deer - University of Alberta
Mus musculus
House mouse
Intended use
To demonstrate feasibility of a gene drive rendering wild deer immune to chronic wasting disease [by spreading PRNP null alleles]
Readiness of Technology
4a - Active research on gene drive construction
Project leader
Westaway D
Institution
University of Alberta, Canada
Publications
Castle et al., 2022
Authors name for system
CRISPR/Cas9 gene drive
Class of Technology
Homing gene drive
Field(s) of application
Other
Description of system
Homing CRISPR
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population modification/replacement