Preliminary work towards a homing CRISPR gene drive in Mus musculus - modelled design III - University of Adelaide

House mouse

Intended use

‘eradication of alien rodents on islands’ to address impacts on bio-diversity; The impacts of rodents on agriculture are also noted as a driver

Readiness of Technology

2b - Gene drive proposed with preliminary laboratory work funded

Project leader

Thomas PQ

Institution

University of Adelaide, Australia

Publications

Authors name for system

‘CRISPR gene drive’ ; ‘Homozygotic embryonic nonviability’

Class of Technology

Homing gene drive

Field(s) of application

Agriculture

Conservation

Description of system

Homing CRISPR – four designs modelled

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication