Proposal for a homing CRISPR gene drive in Trioza eryteae - Pennsylvania State University

African citrus psyllid

Intended use

Reduction in transmission of citrus greening disease, and resulting harm to citrus fruit. This species acts as a vector for Candidatus Liberibacter spp. bacteria which cause the disease.

Readiness of Technology

1 - Gene drive proposed

Project leader

Yang Y

Institution

Pennsylvania State University, USA

Publications

Wheatley and Yang, 2021

Authors name for system

NA – proposal only

Class of Technology

Homing gene drive

Field(s) of application

Agriculture

Description of system

Propose homing CRISPR

For specialists

Description

Propose modification to interfere with capacity to act as vector for begomo-viruses Propose modification or suppression of these psyllids to reduce their capacity to act as vectors.

Notes on readiness of technology

NA – proposal only

Phenotype

NA – proposal only

Authors name for construct(s)

NA – proposal only

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

More than one option proposed