Split homing CRISPR in Culex quinquefasciatus - Pirbright Institute & UC San Diego

Southern house mosquito

Intended use

Reduction of transmission of vector borne diseases in humans, mammals and birds (e.g. avian malaria)

Readiness of Technology

5 - Limited proof of concept in laboratory

Project leader

Alphey L

Institution

Pirbright Institute, UK

Project leader

Esvelt KM

Institution

MIT, USA

Publications

Authors name for system

Split-gene-drive

Class of Technology

Split homing gene drive

Field(s) of application

Vector control

Additional notes

K Esvelt is on DARPA grant award

Description of system

Split homing CRISPR

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

NA - Proof of concept