Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Diptera (true flies)
Culicidae (mosquitoes)
Anopheles (marsh mosquitoes)
No common name
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
NA - preliminary study only
No common name
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of transmission of malaria pathogen by this vector
Type of system
Unspecified CRISPR based gene drive
No common name
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of transmission of malaria pathogen by this vector
Type of system
Not stated
African malaria mosquito
Readiness of Technology
7 - Large cage trialsPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Homing gene drive targeting doublesex gene
African malaria mosquito
Readiness of Technology
7 - Large cage trialsPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
'X-shredder' autosomal sex ratio distorter (I-Ppo 1 based)
African malaria mosquito
Readiness of Technology
6 - Laboratory proof of conceptPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Autosomal sex ratio distorter 'X-shredder' (CRISPR based)
African malaria mosquito
Readiness of Technology
6 - Laboratory proof of conceptPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Homing CRISPR + Sex ratio distorter (X-shredder)
African malaria mosquito
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Homing CRISPR gene drive(s) targeting female fertility genes (including AGAP005958)
African malaria mosquito
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Homing CRISPR gene drive(s) targeting female fertility gene AGAP007280
African malaria mosquito
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Type of system
Homing CRISPR targeting the Agcd gene