Preliminary work towards homing CRISPR in Rhodnius prolixus - London School of Hygiene and Tropical Medicine

Kissing bug

Intended use

Reduction in transmission of the parasite Trypanosoma cruzi by this vector (to reduce occurrence of Chagas disease)

Readiness of Technology

2b - Gene drive proposed with preliminary laboratory work funded

Project leader

Yeo M

Institution

London School of Hygiene and Tropical Medicine

Publications

Authors name for system

NA – no research published yet

Class of Technology

Homing gene drive

Field(s) of application

Vector control

Description of system

Propose homing CRISPR

Description

Proposes deriving ‘insect vectors refractory to disease agents mediated by CRISPR gene drive’.

Notes on readiness of technology

Preliminary research to apply CRISPR based molecular biology tools in this species funded in 2017. Nothing published yet.

Phenotype

NA – no research published yet

Authors name for construct(s)

NA – no research published yet

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement