Preliminary work towards homing CRISPR gene drive targeting 'local fixed alleles' in Mus musculus - North Carolina State University & USDA

House mouse

Intended use

‘Suppressing’ invasive rodents on islands to reduce impacts on biodiversity, agriculture and human health

Readiness of Technology

3 - Preliminary laboratory work published

Project leader

Lloyd AL

Institution

North Carolina State University, USA

Project leader

Piaggio AJ

Institution

USDA APHIS Wildlife Services, USA

Publications

Authors name for system

Localized synthetic gene drive

Field(s) of application

Conservation

Description of system

Homing CRISPR (targeting locally fixed alleles of female fertility genes)

Research in target organism

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Research in model organism

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Intended for release

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