Preliminary work towards a homing CRISPR gene drive in Oryctolagus cuniculus - University of Adelaide

European rabbit

Intended use

Eradication of invasive rabbit populations on islands to address biodiversity impacts; Impacts of rabbits on agriculture are also noted

Readiness of Technology

2a - Gene drive proposed with supporting theoretical work

Project leader

Thomas PQ

Institution

University of Adelaide, Australia

Publications

Authors name for system

CRISPR gene drive; Two variants modelled: ‘Homozygotic embryonic nonviability’ ; ‘Homozygotic XX sterility’

Class of Technology

Homing gene drive

Sex ratio distorter

Field(s) of application

Conservation

Description of system

Homing CRISPR – two variants modelled

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication