Homing CRISPR gene drive targeting female fertility in Mus musculus - University of Adelaide

House mouse

Intended use

‘eradicating mice from islands’ or at continental scale, presumably in Australia, to address their impacts on biodiversity

Readiness of Technology

4a - Active research on gene drive construction

Project leader

Prowse TAA

Institution

University of Adelaide, Australia

Project leader

Thomas PQ

Institution

University of Adelaide, Australia

Publications

Authors name for system

Homing gene drive

Class of Technology

Homing gene drive

Field(s) of application

Conservation

Description of system

Homing CRISPR (targeting ‘haplosufficient female fertility gene’)

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication