Attempt to develop novel homing CRISPR gene drive in Anopheles gambiae - Harvard T.H. Chan School of Public Health

Intended use

Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)

Readiness of Technology

4a - Active research on gene drive construction

Project leader

Catteruccia F

Institution

Harvard T.H. Chan School of Public Health

Project leader

Esvelt K

Institution

MIT, USA

Publications

Authors name for system

Evolutionarily Stable Homing Gene Drive (ESHGD)

Class of Technology

Homing gene drive

Field(s) of application

Vector control

Description of system

Homing CRISPR gene drive variant

Research in target organism

✔

Research in model organism

✖

Intended for release

✖

Intended direct effects

NA - Proof of concept